The Impacts of Prebiotic Supplementation on Humoral and Cell-Mediated Immune Responses of Broilers under Combined Stresses Caused by Feed Restriction and Salmonella enteritidis Challenge

Summary This experiment was conducted to investigate the impacts of prebiotic on humoral and cell-mediated immune responses of broilers under combined stresses caused by feed restriction and Salmonella enteritidis challenge. 320 male broilers (Ross 308) at a 23 factorial arrangement in randomized complete block design were divided into 8 treatment groups with 4 replicates per each. The Impact of these factors and their interaction on cell-mediated immune response to cutaneous basophil hypersensivity (CBH) test, antibody titer response against Newcastle disease virus (NDV) and sheep red blood cell (SRBC), and the relative weight of lymphoid organs were measured. Prebiotic caused an increase and feed restriction caused a decrease in cell-mediated immune responses on days 15 and 30 respectively, and interaction among the factors was differ (P 0.05).