2011•European Journal of Medicinal ChemistryRequires access

Synthesis of lipophilic dimeric C-7/C-7-linked ciprofloxacin and C-6/C-6-linked levofloxacin derivatives. Versatile in vitro biological evaluations of monomeric and dimeric fluoroquinolone derivatives as potential antitumor, antibacterial or antimycobacterial agents

Joëlle Azéma, Brigitte Guidetti, Alexander Korolyov, Róbert Kiss, Christine Roques, Patricia Constant, Mamadou Daffé, Myriam Malet‐Martino

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Key concepts: Chemistry, Lipophilicity, Antimycobacterial, Stereochemistry, Ciprofloxacin, Levofloxacin, Minimum inhibitory concentration, Antibacterial activity

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Synthesis of lipophilic dimeric C-7/C-7-linked ciprofloxacin and C-6/C-6-linked levofloxacin derivatives. Versatile in vitro biological evaluations of monomeric and dimeric fluoroquinolone derivatives as potential antitumor, antibacterial or antimycobacterial agents — Research Paper | ScholarLens