1990•Molecular and Cellular BiochemistryRequires access

Inhibition of transcription by adriamycin is a consequence of the loss of negative superhelicity in DNA mediated by topoisomerase II

M.J. Tarr, Paul D. van Helden

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Key concepts: Topoisomerase, DNA, Transcription (linguistics), RNA, Intercalation (chemistry), Biology, Cleavage (geology), Cytotoxicity

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Inhibition of transcription by adriamycin is a consequence of the loss of negative superhelicity in DNA mediated by topoisomerase II — Research Paper | ScholarLens