New Variant of Varicella-Zoster Virus
Graham A. Tipples, Gwen M. Stephens, Chris Sherlock, Margrit Bowler, Benny Hoy, Darrel A. Cook, Charles F. Grose
Abstract
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Graham A. Tipples, Gwen M. Stephens, Chris Sherlock, Margrit Bowler, Benny Hoy, Darrel A. Cook, Charles F. Grose
Abstract
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In 1998, a varicella-zoster virus glycoprotein E (gE) mutant virus (VZV-MSP) was isolated from a child with chickenpox. VZV-MSP, representing a second VZV serotype, was considered a rarity. We isolated another VZV-MSP-like virus from an elderly man with herpes zoster. These gE mutant viruses may have arisen through independent mutation or may represent a distinct VZV subpopulation that emerged more than 50 years ago.
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In 1998, a varicella-zoster virus glycoprotein E (gE) mutant virus (VZV-MSP) was isolated from a child with chickenpox. VZV-MSP, representing a second VZV serotype, was considered a rarity. We isolated another VZV-MSP-like virus from an elderly man with herpes zoster. These gE mutant viruses may have arisen through independent mutation or may represent a distinct VZV subpopulation that emerged more than 50 years ago.
Key concepts: Varicella zoster virus, Virology, Chickenpox, Virus, Biology, Mutant, Serotype, Genetics