A turn-on fluorescent probe based on hydroxylamine oxidation for detecting ferric ion selectively in living cells
Rui Wang, Fabiao Yu, Ping Liu, Lingxin Chen
Abstract
Rui Wang, Fabiao Yu, Ping Liu, Lingxin Chen
Abstract
We have described a turn on fluorescent probe BOD-NHOH based on hydroxylamine oxidation for detecting intracellular ferric ions. The probe comprises a signal transducer of BODIPY dye and a Fe(3+)-response modulator of hydroxylamine. It is readily employed for assessing intracellular ferric ion levels, and confocal imaging is achieved successfully.
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We have described a turn on fluorescent probe BOD-NHOH based on hydroxylamine oxidation for detecting intracellular ferric ions. The probe comprises a signal transducer of BODIPY dye and a Fe(3+)-response modulator of hydroxylamine. It is readily employed for assessing intracellular ferric ion levels, and confocal imaging is achieved successfully.
Key concepts: Hydroxylamine, Ferric, Fluorescence, Ferric ion, Intracellular, Chemistry, Ion, Turn (biochemistry)