Distribution of Class I Integron among Isolates of Acinetobacter baumannii Recoverd from Burn Patients

B ackground : Acinetobacter baumannii , is an important opportunistic pathogens   responsible   for   nosocomial   infections.   The   aim   of   this experiment  was  to  determine  prevalence  of  Class  I  Integron  in A. baumannii strains isolated from burn patients in Mottahari Hospital and the drug susceptibility pattern. Methods : There were 69 Acinetobacter isolates, 68 (98.5%) were identified as A . baumannii . Antimicrobial susceptibility of these isolates were determined by a disk diffusion method. PCR assay for detection of bla OXA-51 like gene (for identity confirmation) and intI was performed. R esults : The  most  effective  antibiotic  for  treating A.  baumannii was colistin, followed by tetracyclin and tobramycin. The presence of Integron class  I  was  detected  in  14.49%  of  isolates.  ESBL  and  carbapenemase production were observed in 10% and 24.6% of isolates, respectively. Conclusion : Due to the high resistance of strains lacking Integron I, the findings are although class I integrons are disseminated among clinical isolates  of A.  baumannii ,  at  present  research,  they  they  do  not  play important role in dissemination of antibiotic resistance genes in Mottahari Hospital in Tehran, Iran.