Immunohistochemical and Ultrastructural Characterization of Granular Cell Tumors of the Female Reproductive Tract in Two Aged Wistar Rats

Granular cell tumors of the reproductive tract in rodents granules with indistinct cell borders and were separated by have been reported primarily in the uterine cervix of mice collagen bundles or smooth muscle cells (Fig. 3). Scattered treated with estrogens.> Spontaneous cervical and vaginal within the mass were foci of perivascular and interstitial granular cell tumors occur rarely in the Fischer rat.' We mononuclear cell infiltrates. Both granular cell tumors were describe histopathologic, immunohistochemical, and ultra- periodic acid-Schiff positive and diastase resistant (Fig. 4) structural features of granular cell tumors in the uterine cer- and stained faintly with Alcian blue. Both tumors stained