2000•Annals of OncologyOpen access

Immunohistochemical determination of p53 protein does not predict clinical response in advanced colorectal cancer with low thymidylate synthase expression receiving a bolus 5-fluorouracil—leucovorin combination

Stefano Cascinu, Vincenzo Catalano, Carlo Aschele, Sandro Barni, Domizia Debernardis, Luigi Gallo, Roberto Bandelloni, Maria Pia Staccioli, Anna Maria Baldelli, A. Brenna, Andrea Valenti, Pietro Muretto, G. Catalano

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Key concepts: Thymidylate synthase, Medicine, Fluorouracil, Bolus (digestion), Colorectal cancer, Immunohistochemistry, Internal medicine, Population