1961American Journal of Physiology-Legacy ContentRequires access

Effect of hemorrhage on LD100 of dog following supralethal dose of total body gamma radiation

Stanley W. Handford, Paul W. Johnson

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Abstract

To test the effect of hemorrhage on survival following wholebody exposure to a supralethal dose of radiation, three groups of dogs were bled 25% of their estimated blood volume. In group 1, bleeding was accomplished immediately before irradiation; in groups 2 and 3, 30 min and 48 hr, respectively, following irradiation. No significant alterations in the course of acute radiation sickness or survival time (LD100) were observed.

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What this paper is about

To test the effect of hemorrhage on survival following wholebody exposure to a supralethal dose of radiation, three groups of dogs were bled 25% of their estimated blood volume. In group 1, bleeding was accomplished immediately before irradiation; in groups 2 and 3, 30 min and 48 hr, respectively, following irradiation. No significant alterations in the course of acute radiation sickness or survival time (LD100) were observed.

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Available abstract

To test the effect of hemorrhage on survival following wholebody exposure to a supralethal dose of radiation, three groups of dogs were bled 25% of their estimated blood volume. In group 1, bleeding was accomplished immediately before irradiation; in groups 2 and 3, 30 min and 48 hr, respectively, following irradiation. No significant alterations in the course of acute radiation sickness or survival time (LD100) were observed.

Key concepts: Radiation sickness, Nuclear medicine, Medicine, Irradiation, Radiation dose, Body weight, Anesthesia, Internal medicine

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