1982•Journal of Antimicrobial ChemotherapyRequires access

Combined activity of ketoconazole and sulphamethoxazole against Candida albicans

William H. Beggs

Open publisher page 10 citations

Abstract

Weak fungistatic concentrations of ketoconazole were tested in combination with a subinhibitory level of sulphamethoxazole against five strains of Candida albicans in vitro. In each case combined drug activity markedly surpassed that seen with ketoconazole alone. It was concluded that this drug pair can act synergistically against Can. albicans.

About this research paper

What this paper is about

Weak fungistatic concentrations of ketoconazole were tested in combination with a subinhibitory level of sulphamethoxazole against five strains of Candida albicans in vitro. In each case combined drug activity markedly surpassed that seen with ketoconazole alone. It was concluded that this drug pair can act synergistically against Can. albicans.

Why it matters

OpenAlex reports 10 citations for this work. Citation counts describe recorded attention and do not establish research quality.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Weak fungistatic concentrations of ketoconazole were tested in combination with a subinhibitory level of sulphamethoxazole against five strains of Candida albicans in vitro. In each case combined drug activity markedly surpassed that seen with ketoconazole alone. It was concluded that this drug pair can act synergistically against Can. albicans.

Key concepts: Ketoconazole, Candida albicans, Microbiology, Corpus albicans, In vitro, Drug, Pharmacology, Biology

Related papers

Back to paper searchBrowse research topicsOriginal source
Combined activity of ketoconazole and sulphamethoxazole against Candida albicans — Research Paper | ScholarLens