2012•Journal of Pharmaceutical SciencesRequires access

Differential Selectivity of Efflux Transporter Inhibitors in Caco-2 and MDCK–MDR1 Monolayers: A Strategy to Assess the Interaction of a New Chemical Entity with P-gp, BCRP, and MRP2

Kirsten Mease, Rucha Sane, Lalitha Podila, Mitchell E. Taub

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Key concepts: Efflux, Multidrug resistance-associated protein 2, Caco-2, Transporter, Chemistry, Selectivity, P-glycoprotein, ATP-binding cassette transporter

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Differential Selectivity of Efflux Transporter Inhibitors in Caco-2 and MDCK–MDR1 Monolayers: A Strategy to Assess the Interaction of a New Chemical Entity with P-gp, BCRP, and MRP2 — Research Paper | ScholarLens