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2011•Helvetica Chimica ActaRequires access

Isoprenoids and Flavonoids with Antimicrobial Activity from Ficus conraui Warburg (Moraceae)

Rodrigue T. Kengap, Gilbert Deccaux Wabo Fotso Kapche, Jean Paul Dzoyem, Ingrid Konga Simo, Pantaléon Ambassa, Louis P. Sandjo, Berhanu M. Abegaz, Bonaventure T. Ngadjui

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Abstract

Abstract A new triterpene, conrauidienol ( 1 ), and a new dihydroflavonol, conrauiflavonol ( 2 ), along with β ‐amyrin acetate ( 3 ), betulinic acid ( 4 ), ursolic acid ( 5 ), 6 β ‐hydroxystigmasta‐4,22‐dien‐3‐one ( 6 ), 8‐prenylapigenin ( 7 ), β ‐sitosterol glucoside ( 8 ), and 3,4′,5‐trihydroxy‐6″,6″‐dimethylpyrano[2,3‐g]flavone ( 9 ) were isolated from the stem barks of Ficus conraui Warburg (Moraceae). Their structures were elucidated by spectroscopic analysis. The hexane, AcOEt, and MeOH extracts, as well as the new isolated compounds exhibited selective antimicrobial activities varying from weak to moderate.

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What this paper is about

Abstract A new triterpene, conrauidienol ( 1 ), and a new dihydroflavonol, conrauiflavonol ( 2 ), along with β ‐amyrin acetate ( 3 ), betulinic acid ( 4 ), ursolic acid ( 5 ), 6 β ‐hydroxystigmasta‐4,22‐dien‐3‐one ( 6 ), 8‐prenylapigenin ( 7 ), β ‐sitosterol glucoside ( 8 ), and 3,4′,5‐trihydroxy‐6″,6″‐dimethylpyrano[2,3‐g]flavone ( 9 ) were isolated from the stem barks of Ficus conraui Warburg (Moraceae). Their structures were elucidated by spectroscopic analysis. The hexane, AcOEt, and MeOH extracts, as well as the new isolated compounds exhibited selective antimicrobial activities varying from weak to moderate.

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Available abstract

Abstract A new triterpene, conrauidienol ( 1 ), and a new dihydroflavonol, conrauiflavonol ( 2 ), along with β ‐amyrin acetate ( 3 ), betulinic acid ( 4 ), ursolic acid ( 5 ), 6 β ‐hydroxystigmasta‐4,22‐dien‐3‐one ( 6 ), 8‐prenylapigenin ( 7 ), β ‐sitosterol glucoside ( 8 ), and 3,4′,5‐trihydroxy‐6″,6″‐dimethylpyrano[2,3‐g]flavone ( 9 ) were isolated from the stem barks of Ficus conraui Warburg (Moraceae). Their structures were elucidated by spectroscopic analysis. The hexane, AcOEt, and MeOH extracts, as well as the new isolated compounds exhibited selective antimicrobial activities varying from weak to moderate.

Key concepts: Moraceae, Betulinic acid, Chemistry, Ursolic acid, Antimicrobial, Triterpene, Terpene, Stereochemistry

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Isoprenoids and Flavonoids with Antimicrobial Activity from Ficus conraui Warburg (Moraceae) — Research Paper | ScholarLens