1963•Journal of General MicrobiologyRequires access

Spontaneous Mutation in Spheroplasts of Escherichia colid

Francis J. Ryan, Toshihiko Okada, Takako Nagata

Abstract

SUMMARY: Spheroplast suspensions containing as few as one rod in a thousand were made with Escherichia coli (15 his -) by the use of penicillin. These spheroplasts could be reverted to the rod state with efficiency approaching 100%. Spontaneous mutation from histidine requirement to non-requirement was observed in these spheroplasts, in which cell division did not take place.

About this research paper

What this paper is about

Why it matters

OpenAlex reports 30 citations for this work. Citation counts describe recorded attention and do not establish research quality.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Key concepts: Spheroplast, Escherichia coli, Mutation, Biology, Microbiology, Chemistry, Genetics, Gene