Definitions of Cytomegalovirus Infection and Disease in Transplant Recipients
Per Ljungman, Paul Griffiths, Carlos V. Payá
Abstract
Per Ljungman, Paul Griffiths, Carlos V. Payá
Abstract
Cytomegalovirus (CMV) infection and disease are important causes of morbidity and mortality among transplant recipients. For the purpose of developing consistent reporting of CMV in clinical trials, definitions of CMV infection and disease were developed and published. This study seeks to update the definitions of CMV on the basis of recent developments in diagnostic techniques, as well as to add to these definitions the concept of indirect effects caused by CMV.
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Cytomegalovirus (CMV) infection and disease are important causes of morbidity and mortality among transplant recipients. For the purpose of developing consistent reporting of CMV in clinical trials, definitions of CMV infection and disease were developed and published. This study seeks to update the definitions of CMV on the basis of recent developments in diagnostic techniques, as well as to add to these definitions the concept of indirect effects caused by CMV.
Key concepts: Medicine, Cytomegalovirus infection, Cytomegalovirus, Disease, Immunology, Intensive care medicine, Cytomegalovirus infections, Betaherpesvirinae