ScholarLens Back to search
2003•The Journals of Gerontology Series AOpen access

Increased Prevalence of Peripheral Arterial Disease in Older Men and Women With Subclinical Hypothyroidism

Maung Maung Mya, Wilbert S. Aronow

Open full text 42 citations

Abstract

BACKGROUND: We report the prevalence of symptomatic peripheral arterial disease (PAD) associated with subclinical hypothyroidism in older persons. METHODS: We investigated the association of subclinical hypothyroidism with symptomatic PAD in 18 persons (16 women and 2 men) with subclinical hypothyroidism and in 231 euthyroid persons (151 women and 96 men), mean age 79 +/- 9 years, in an academic nursing home. RESULTS: Symptomatic PAD was present in 14 of 18 persons (78%) with subclinical hypothyroidism and in 40 of 231 euthyroid persons (17%; p <.0001, comparing subclinical hypothyroidism with euthyroidism). Symptomatic PAD was present in 13 of 16 women (81%) and in 1 of 2 men (50%) with subclinical hypothyroidism (p was not significant). CONCLUSIONS: Subclinical hypothyroidism was associated with a high prevalence of symptomatic PAD in elderly men and women.

Open-access reader

About this research paper

What this paper is about

BACKGROUND: We report the prevalence of symptomatic peripheral arterial disease (PAD) associated with subclinical hypothyroidism in older persons. METHODS: We investigated the association of subclinical hypothyroidism with symptomatic PAD in 18 persons (16 women and 2 men) with subclinical hypothyroidism and in 231 euthyroid persons (151 women and 96 men), mean age 79 +/- 9 years, in an academic nursing home. RESULTS: Symptomatic PAD was present in 14 of 18 persons (78%) with subclinical hypothyroidism and in 40 of 231 euthyroid persons (17%; p <.0001, comparing subclinical hypothyroidism with euthyroidism). Symptomatic PAD was present in 13 of 16 women (81%) and in 1 of 2 men (50%) with subclinical hypothyroidism (p was not significant). CONCLUSIONS: Subclinical hypothyroidism was associated with a high prevalence of symptomatic PAD in elderly men and women.

Why it matters

OpenAlex reports 42 citations for this work. Citation counts describe recorded attention and do not establish research quality.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

BACKGROUND: We report the prevalence of symptomatic peripheral arterial disease (PAD) associated with subclinical hypothyroidism in older persons. METHODS: We investigated the association of subclinical hypothyroidism with symptomatic PAD in 18 persons (16 women and 2 men) with subclinical hypothyroidism and in 231 euthyroid persons (151 women and 96 men), mean age 79 +/- 9 years, in an academic nursing home. RESULTS: Symptomatic PAD was present in 14 of 18 persons (78%) with subclinical hypothyroidism and in 40 of 231 euthyroid persons (17%; p <.0001, comparing subclinical hypothyroidism with euthyroidism). Symptomatic PAD was present in 13 of 16 women (81%) and in 1 of 2 men (50%) with subclinical hypothyroidism (p was not significant). CONCLUSIONS: Subclinical hypothyroidism was associated with a high prevalence of symptomatic PAD in elderly men and women.

Key concepts: Subclinical infection, Euthyroid, Medicine, Peripheral, Internal medicine, Disease, Thyroid disease, Pediatrics

Related papers

Related paper 1Related paper 2Related paper 3
Back to paper searchBrowse research topicsOriginal source
Increased Prevalence of Peripheral Arterial Disease in Older Men and Women With Subclinical Hypothyroidism — Research Paper | ScholarLens