The Effect of Weight Loss on a Stable Biomarker of Inflammation, C-Reactive Protein

Inflammation is pivotal in all phases of atherosclerosis. Increasing body weight is positively associated with inflammation. Weight loss studies have shown that decreasing body weight significantly decreases C-reactive protein, the prototypic biomarker for inflammation. Reducing inflammation through weight loss could therefore be associated with reduced risk for cardiovascular disease and other obesity-associated chronic diseases.