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2008•Critical CareOpen access

Measurement of procalcitonin in bronchoalveolar lavage and serum as early predictors in acute respiratory distress syndrome

Assem Abdel Razek, Emad Arida, Akram Deghady

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Abstract

Procalcitonin (PCT) is a diagnostic for identifying severe bacterial infections and reliably indicating complications secondary to systemic inflammation. PCT levels increase in cases of sepsis, septic shock and in severe systemic inflammatory reactions. The early pathological features of acute respiratory distress syndrome (ARDS) are generally described as diffuse alveolar damage, which can be diagnosed by cytological examination of bronchoalveolar lavage fluid (BAL) [ 1 ]. The aim of this study was to evaluate the value of PCT measurement in BAL and serum in the early diagnosis, and to faciliate reliable follow-up of the clinical course of ARDS.

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Procalcitonin (PCT) is a diagnostic for identifying severe bacterial infections and reliably indicating complications secondary to systemic inflammation. PCT levels increase in cases of sepsis, septic shock and in severe systemic inflammatory reactions. The early pathological features of acute respiratory distress syndrome (ARDS) are generally described as diffuse alveolar damage, which can be diagnosed by cytological examination of bronchoalveolar lavage fluid (BAL) [ 1 ]. The aim of this study was to evaluate the value of PCT measurement in BAL and serum in the early diagnosis, and to faciliate reliable follow-up of the clinical course of ARDS.

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Available abstract

Procalcitonin (PCT) is a diagnostic for identifying severe bacterial infections and reliably indicating complications secondary to systemic inflammation. PCT levels increase in cases of sepsis, septic shock and in severe systemic inflammatory reactions. The early pathological features of acute respiratory distress syndrome (ARDS) are generally described as diffuse alveolar damage, which can be diagnosed by cytological examination of bronchoalveolar lavage fluid (BAL) [ 1 ]. The aim of this study was to evaluate the value of PCT measurement in BAL and serum in the early diagnosis, and to faciliate reliable follow-up of the clinical course of ARDS.

Key concepts: Procalcitonin, Medicine, ARDS, Bronchoalveolar lavage, Acute respiratory distress, Sepsis, Respiratory distress, Pathological

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