ScholarLens Back to search
2002•Clinical & Laboratory HaematologyRequires access

Automated counting of nucleated red blood cells in blood samples of newborns

Marinus H. de Keijzer, W. van der Meer

Open publisher page 21 citations

Abstract

Nucleated red blood cells (NRBC) in blood samples interfere with the white blood cell (WBC) count on many types of automated haematology analysers. This makes it necessary to correct the WBC count by counting NRBC microscopically. This report describes the evaluation of two analysers, the Cell-Dyn 4000 and the Sysmex XE-2100, which use new techniques to recognize and enumerate NRBC. We conclude that both the Cell-Dyn 4000 and the Sysmex XE-2100 give an accurate WBC count in the presence of NRBC. Furthermore, they can enumerate NRBC correctly when compared with microscopic observation.

About this research paper

What this paper is about

Nucleated red blood cells (NRBC) in blood samples interfere with the white blood cell (WBC) count on many types of automated haematology analysers. This makes it necessary to correct the WBC count by counting NRBC microscopically. This report describes the evaluation of two analysers, the Cell-Dyn 4000 and the Sysmex XE-2100, which use new techniques to recognize and enumerate NRBC. We conclude that both the Cell-Dyn 4000 and the Sysmex XE-2100 give an accurate WBC count in the presence of NRBC. Furthermore, they can enumerate NRBC correctly when compared with microscopic observation.

Why it matters

OpenAlex reports 21 citations for this work. Citation counts describe recorded attention and do not establish research quality.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Nucleated red blood cells (NRBC) in blood samples interfere with the white blood cell (WBC) count on many types of automated haematology analysers. This makes it necessary to correct the WBC count by counting NRBC microscopically. This report describes the evaluation of two analysers, the Cell-Dyn 4000 and the Sysmex XE-2100, which use new techniques to recognize and enumerate NRBC. We conclude that both the Cell-Dyn 4000 and the Sysmex XE-2100 give an accurate WBC count in the presence of NRBC. Furthermore, they can enumerate NRBC correctly when compared with microscopic observation.

Key concepts: Nucleated Red Blood Cell, Hematology analyzer, Blood cell, Blood smear, White blood cell, Red blood cell, Hematology, Medicine

Related papers

Related paper 1Related paper 2
Back to paper searchBrowse research topicsOriginal source
Automated counting of nucleated red blood cells in blood samples of newborns — Research Paper | ScholarLens