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Valvular Heart Disease Caused By Chinese Preprietary Slimming Medicine Adulterated With Fenfluramine

KSK Chang, Twl Mak, Lana Kwong, Kt So

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Abstract

Anorectic drugs containing fenfluramine and dexfenfluramine have been classified as 'off-label' drugs in Hong Kong for several years. In this study, we report a case of valvular heart disease found in a teenager who had been taking Chinese proprietary medicine as a weight reducing agent for six months. Fenfluramine was identified in the diet pills. Two other herbal proprietary slimming products adulterated with fenfluramine and affecting several hundred people were subsequently discovered.

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What this paper is about

Anorectic drugs containing fenfluramine and dexfenfluramine have been classified as 'off-label' drugs in Hong Kong for several years. In this study, we report a case of valvular heart disease found in a teenager who had been taking Chinese proprietary medicine as a weight reducing agent for six months. Fenfluramine was identified in the diet pills. Two other herbal proprietary slimming products adulterated with fenfluramine and affecting several hundred people were subsequently discovered.

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OpenAlex reports 3 citations for this work. Citation counts describe recorded attention and do not establish research quality.

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Available abstract

Anorectic drugs containing fenfluramine and dexfenfluramine have been classified as 'off-label' drugs in Hong Kong for several years. In this study, we report a case of valvular heart disease found in a teenager who had been taking Chinese proprietary medicine as a weight reducing agent for six months. Fenfluramine was identified in the diet pills. Two other herbal proprietary slimming products adulterated with fenfluramine and affecting several hundred people were subsequently discovered.

Key concepts: Fenfluramine, Dexfenfluramine, Anorectic, Medicine, Pill, valvular heart disease, Heart disease, Phentermine

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