2007•The American Journal of Human GeneticsOpen access

RAD51 135G→C Modifies Breast Cancer Risk among BRCA2 Mutation Carriers: Results from a Combined Analysis of 19 Studies

Antonis C. Antoniou, Olga M. Sinilnikova, Jacques Simard, Mélanie Léoné, Martine Dumont, Susan L. Neuhausen, Jeffery P. Struewing, Dominique Stoppa‐Lyonnet, Laure Barjhoux, David J. Hughes, Isabelle Coupier, Muriel Belotti, Christine Lasset, Valérie Bonadona, Yves-Jean Bignon, Timothy R. Rebbeck, Theresa Maria Wagner, Henry T. Lynch, Susan M. Domchek, Katherine L. Nathanson, Judy Ellen Garber, Jeffrey N. Weitzel, Steven Alexander Narod, Gail Elizabeth Tomlinson, Olufunmilayo Ibironke Olopade, Andrew K. Godwin, Claudine J. Isaacs, Anna Jakubowska, Jan Lubiński, Jacek Gronwald, Bohdan Górski, Tomasz Byrski, Tomasz Huzarski, Susan Peock, Margaret Cook, Caroline Baynes, Alexandra Murray, Mark Rogers, Peter A. Daly, Huw Dorkins, Rita K. Schmutzler, Beatrix Versmold, Christoph Engel, Alfons Meindl, Norbert Arnold, Dieter Niederacher, Helmut Deissler, Amanda B. Spurdle, Xiaoqing Chen, Nicola Waddell, Nicole Cloonan, Tomas Kirchhoff, Kenneth Offit, Eitan Friedman, Bella Kaufmann, Yael Laitman, Gilli Galore, Gad Rennert, Flavio Lejbkowicz, Leon Raskin, Irene Louise Andrulis, Eduard Ilyushik, Hilmi Özçelik, Peter Devilee, Maaike P.G. Vreeswijk, M H Greene, Sheila Ann Prindiville, Ana Osório, Javier Benítez, Michal Zikán, Csilla I. Szabo, Outi Kilpivaara, Heli A. Nevanlinna, Ute Hamann, Francine Durocher, Aðalgeir Arason, Fergus J. Couch, Douglas F. Easton, Georgia Chenevix‐Trench

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Key concepts: Heterozygote advantage, RAD51, Breast cancer, Genotype, SNP, Mutation, Hazard ratio, Oncology

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RAD51 135G→C Modifies Breast Cancer Risk among BRCA2 Mutation Carriers: Results from a Combined Analysis of 19 Studies — Research Paper | ScholarLens