2012Journal of Lower Genital Tract DiseaseRequires access

A Case of Parametrial Lymph Node Involvement in Stage IA2 Squamous Cell Carcinoma of the Cervix Treated With Radical Hysterectomy and a Review of the Literature

Caroline C. Billingsley, Matthew F. Kohler, William T. Creasman, James E. Madory, Jennifer L. Young

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Abstract

In Brief Cervical cancer classified as stage IA2 and IB1 according to the International Federation of Gynecology and Obstetrics has historically been treated with radical hysterectomy and bilateral lymph node dissection, but recent recommendations suggest more conservative treatment modalities. We report a woman with stage IA2 cervical cancer at low risk for parametrial spread including no lymphovascular space invasion, clear conization margins, and tumor size less than 2 cm, who underwent radical hysterectomy and was found to have a single positive metastatic parametrial lymph node. This case report is an important reminder that parametrial involvement occurs in low-risk early-stage cervical cancers. It is imperative that patients are informed of the possibility of parametrial involvement and possible sequelae of suboptimal management when parametrectomy is omitted in radical hysterectomies.

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In Brief Cervical cancer classified as stage IA2 and IB1 according to the International Federation of Gynecology and Obstetrics has historically been treated with radical hysterectomy and bilateral lymph node dissection, but recent recommendations suggest more conservative treatment modalities. We report a woman with stage IA2 cervical cancer at low risk for parametrial spread including no lymphovascular space invasion, clear conization margins, and tumor size less than 2 cm, who underwent radical hysterectomy and was found to have a single positive metastatic parametrial lymph node. This case report is an important reminder that parametrial involvement occurs in low-risk early-stage cervical cancers. It is imperative that patients are informed of the possibility of parametrial involvement and possible sequelae of suboptimal management when parametrectomy is omitted in radical hysterectomies.

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Available abstract

In Brief Cervical cancer classified as stage IA2 and IB1 according to the International Federation of Gynecology and Obstetrics has historically been treated with radical hysterectomy and bilateral lymph node dissection, but recent recommendations suggest more conservative treatment modalities. We report a woman with stage IA2 cervical cancer at low risk for parametrial spread including no lymphovascular space invasion, clear conization margins, and tumor size less than 2 cm, who underwent radical hysterectomy and was found to have a single positive metastatic parametrial lymph node. This case report is an important reminder that parametrial involvement occurs in low-risk early-stage cervical cancers. It is imperative that patients are informed of the possibility of parametrial involvement and possible sequelae of suboptimal management when parametrectomy is omitted in radical hysterectomies.

Key concepts: Parametrial, Medicine, Radical Hysterectomy, Cervical cancer, Lymph node, Cervix, Stage (stratigraphy), Hysterectomy

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A Case of Parametrial Lymph Node Involvement in Stage IA2 Squamous Cell Carcinoma of the Cervix Treated With Radical Hysterectomy and a Review of the Literature — Research Paper | ScholarLens