Efficient Synthesis of Bis(heterocyclyl)methanes
Kamaljit Singh, Shivali Sharma, Amit Sharma
Abstract
Kamaljit Singh, Shivali Sharma, Amit Sharma
Abstract
The reaction of pyrrole/furan aldehyde with Grignard reagent and pyrrole/N-methyl pyrrole in sequence allows efficient synthesis of a number of meso-elaborated bis(heterocyclyl)methanes, which are otherwise difficult to obtain through a direct aldehyde condensation route.
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The reaction of pyrrole/furan aldehyde with Grignard reagent and pyrrole/N-methyl pyrrole in sequence allows efficient synthesis of a number of meso-elaborated bis(heterocyclyl)methanes, which are otherwise difficult to obtain through a direct aldehyde condensation route.
Key concepts: Chemistry, Aldehyde, Pyrrole, Furan, Reagent, Condensation, Sequence (biology), Organic chemistry