2011Synthetic CommunicationsRequires access

Efficient Synthesis of Bis(heterocyclyl)methanes

Kamaljit Singh, Shivali Sharma, Amit Sharma

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Abstract

The reaction of pyrrole/furan aldehyde with Grignard reagent and pyrrole/N-methyl pyrrole in sequence allows efficient synthesis of a number of meso-elaborated bis(heterocyclyl)methanes, which are otherwise difficult to obtain through a direct aldehyde condensation route.

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What this paper is about

The reaction of pyrrole/furan aldehyde with Grignard reagent and pyrrole/N-methyl pyrrole in sequence allows efficient synthesis of a number of meso-elaborated bis(heterocyclyl)methanes, which are otherwise difficult to obtain through a direct aldehyde condensation route.

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Available abstract

The reaction of pyrrole/furan aldehyde with Grignard reagent and pyrrole/N-methyl pyrrole in sequence allows efficient synthesis of a number of meso-elaborated bis(heterocyclyl)methanes, which are otherwise difficult to obtain through a direct aldehyde condensation route.

Key concepts: Chemistry, Aldehyde, Pyrrole, Furan, Reagent, Condensation, Sequence (biology), Organic chemistry

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