2000•Journal of Investigative DermatologyOpen access

13-cis Retinoic Acid Exerts its Specific Activity on Human Sebocytes through Selective Intracellular Isomerization to All-trans Retinoic Acid and Binding to Retinoid Acid Receptors

Miki Tsukada, Mandy Schröder, Constantin E. Orfanos, Christos C. Zouboulis, Thomas C. Roos, Roshantha A.S. Chandraratna, Uwe Reichert, Hans F. Merk

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Key concepts: Retinoic acid, Retinoic acid-inducible orphan G protein-coupled receptor, Retinoic acid receptor gamma, Retinoic acid receptor beta, Retinoic acid receptor, Retinoid X receptor gamma, Retinoid, Tretinoin