Tetrabenazine in the treatment of severe pediatric chorea
Anjan Kumar Chatterjee, Steven J. Frucht
Abstract
Anjan Kumar Chatterjee, Steven J. Frucht
Abstract
Tetrabenazine (TBZ) is widely used to treat adults with hyperkinetic movement disorders; however, published experience with the drug in pediatric patients is limited. We report on 5 children with severe chorea who were treated with TBZ. TBZ effectively controlled chorea in 4 patients, and despite the need for relatively high doses, it was well tolerated.
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Tetrabenazine (TBZ) is widely used to treat adults with hyperkinetic movement disorders; however, published experience with the drug in pediatric patients is limited. We report on 5 children with severe chorea who were treated with TBZ. TBZ effectively controlled chorea in 4 patients, and despite the need for relatively high doses, it was well tolerated.
Key concepts: Tetrabenazine, Chorea, Movement disorders, Medicine, Pediatrics, Psychiatry, Internal medicine, Disease