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1999•Emerging infectious diseasesOpen access

Acute Sin Nombre Hantavirus Infection without Pulmonary Syndrome, United States

Paul Kitsutani, Robert Denton, Curtis L. Fritz, Robert Murray, Randall L. Todd, W. John Pape, Jon Frampton, Joni C. Young, Ali S. Khan, C. J. Peters, Thomas G. Ksiazek

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Abstract

Hantavirus pulmonary syndrome (HPS) occurs in most infections with Sin Nombre virus and other North American hantaviruses. We report five cases of acute hantavirus infection that did not fit the HPS case definition. The patients had characteristic prodromal symptoms without severe pulmonary involvement. These cases suggest that surveillance for HPS may need to be expanded.

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What this paper is about

Hantavirus pulmonary syndrome (HPS) occurs in most infections with Sin Nombre virus and other North American hantaviruses. We report five cases of acute hantavirus infection that did not fit the HPS case definition. The patients had characteristic prodromal symptoms without severe pulmonary involvement. These cases suggest that surveillance for HPS may need to be expanded.

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Available abstract

Hantavirus pulmonary syndrome (HPS) occurs in most infections with Sin Nombre virus and other North American hantaviruses. We report five cases of acute hantavirus infection that did not fit the HPS case definition. The patients had characteristic prodromal symptoms without severe pulmonary involvement. These cases suggest that surveillance for HPS may need to be expanded.

Key concepts: Hantavirus pulmonary syndrome, Hantavirus, Hantavirus Infection, Medicine, Pulmonary infection, Virology, Coronavirus disease 2019 (COVID-19), Immunology

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