Mucosa-associated lymphoid tissue lymphoma in conjunctiva
SantoshKumar Mondal
Abstract
SantoshKumar Mondal
Abstract
A case of primary mucosa-associated lymphoid tissue (MALT) lymphoma (marginal zone B-cell lymphoma of MALT according to WHO classification) in conjunctiva, which presented as a slowly growing salmon-colored mass at limbus of left eye is reported. Histological examination revealed a diffuse low-grade lymphoma. Immunohistochemical analysis using monoclonal antibodies showed that the tumor cells are leukocyte common antigen (CD45)+, CD20+, CD3-, CD5-, CD10- and CD43-, which confirmed the B-cell lineage of lymphoma. The case is being reported for its rarity and clinical importance of recognizing such cases because of excellent prognosis.
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A case of primary mucosa-associated lymphoid tissue (MALT) lymphoma (marginal zone B-cell lymphoma of MALT according to WHO classification) in conjunctiva, which presented as a slowly growing salmon-colored mass at limbus of left eye is reported. Histological examination revealed a diffuse low-grade lymphoma. Immunohistochemical analysis using monoclonal antibodies showed that the tumor cells are leukocyte common antigen (CD45)+, CD20+, CD3-, CD5-, CD10- and CD43-, which confirmed the B-cell lineage of lymphoma. The case is being reported for its rarity and clinical importance of recognizing such cases because of excellent prognosis.
Key concepts: Conjunctiva, Lymphatic system, Lymphoma, Pathology, Mucosa-associated lymphoid tissue, Medicine, MALT lymphoma, Biology