1979•Scandinavian Journal of HaematologyRequires access
Massive Platelet Transfusion after Splenectomy in a Case of Myelofibrosis
Francis Toolis, Lewis W. Paton
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Abstract
A patient with myelofibrosis complicated by massive splenomegaly underwent splenectomy to alleviate the increasing transfusion requirements and iron overload. The platelets exhibited qualitative defects pre-operatively. Following splenectomy the patient bled profusely and required massive blood and platelet transfusions. The postoperative haemorrhage was controlled by giving sufficient platelets to normalize the platelet aggregation.