1974Antimicrobial Agents and ChemotherapyOpen access

Isolation and Characterization of a Kanamycin Resistance Plasmid from Staphylococcus aureus

Paul W. Stiffler, Helen M. Sweeney, Marc Schneider, Sidney Cohen

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Abstract

A circular covalently closed duplex deoxyribonucleic acid plasmid carrying genes for resistance to kanamycin/neomycin has been identified in Staphylococcus aureus E419. The plasmid has a molecular size of 9.2 x 10(6) daltons and can be transduced into or can transform competent susceptible strains of S. aureus to kanamycin/neomycin resistance.

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A circular covalently closed duplex deoxyribonucleic acid plasmid carrying genes for resistance to kanamycin/neomycin has been identified in Staphylococcus aureus E419. The plasmid has a molecular size of 9.2 x 10(6) daltons and can be transduced into or can transform competent susceptible strains of S. aureus to kanamycin/neomycin resistance.

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Available abstract

A circular covalently closed duplex deoxyribonucleic acid plasmid carrying genes for resistance to kanamycin/neomycin has been identified in Staphylococcus aureus E419. The plasmid has a molecular size of 9.2 x 10(6) daltons and can be transduced into or can transform competent susceptible strains of S. aureus to kanamycin/neomycin resistance.

Key concepts: Kanamycin, Plasmid, Neomycin, Staphylococcus aureus, Microbiology, Antibiotics, Biology, Gene

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