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Preliminary Evaluation of Several Chelating Agents for Plutonium Removal

J.E. Ballou

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Abstract

Preliminary tests indicate the chelating agent triethylenetetraminehexaacetic acid (TTHA) is as effective as diethylenetriaminepentaacetic acid (DTPA) in plutonium removal. TTHA appears to be even more effective than DTPA when the agents are administered orally. The range of toxicity and the optimum dosage levels of TTHA have not yet been clearly defined. Two additional chelating agents, aminoethylcyclohexyldiaminepentaacetic acid (ACHDPA) and aminoethoxycyclohexylaminetetraacetic acid (ACHTA), although structurally similar to DTPA, were considerably less effective than DTPA in plutonium removal.

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What this paper is about

Preliminary tests indicate the chelating agent triethylenetetraminehexaacetic acid (TTHA) is as effective as diethylenetriaminepentaacetic acid (DTPA) in plutonium removal. TTHA appears to be even more effective than DTPA when the agents are administered orally. The range of toxicity and the optimum dosage levels of TTHA have not yet been clearly defined. Two additional chelating agents, aminoethylcyclohexyldiaminepentaacetic acid (ACHDPA) and aminoethoxycyclohexylaminetetraacetic acid (ACHTA), although structurally similar to DTPA, were considerably less effective than DTPA in plutonium removal.

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Available abstract

Preliminary tests indicate the chelating agent triethylenetetraminehexaacetic acid (TTHA) is as effective as diethylenetriaminepentaacetic acid (DTPA) in plutonium removal. TTHA appears to be even more effective than DTPA when the agents are administered orally. The range of toxicity and the optimum dosage levels of TTHA have not yet been clearly defined. Two additional chelating agents, aminoethylcyclohexyldiaminepentaacetic acid (ACHDPA) and aminoethoxycyclohexylaminetetraacetic acid (ACHTA), although structurally similar to DTPA, were considerably less effective than DTPA in plutonium removal.

Key concepts: Diethylenetriaminepentaacetic acid, Plutonium, Chelation, Chemistry, Toxicity, Radiochemistry, Pentetic acid, Edetic Acid

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