2008•New England Journal of MedicineRequires access

Monoclonal Antibody Therapy for B-Cell Non-Hodgkin's Lymphoma

Bruce D. Cheson, John Paul Leonard

Open publisher page 439 citations

Abstract

Treatment of B-cell non-Hodgkin's lymphoma has become more successful, largely owing to the availability of therapeutic monoclonal antibodies, which may avoid the toxic effects of chemotherapy, improve the outcomes when combined with chemotherapy, and provide options for patients with refractory disease. This article reviews the current uses of monoclonal antibodies in B-cell non-Hodgkin's lymphoma.

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What this paper is about

Treatment of B-cell non-Hodgkin's lymphoma has become more successful, largely owing to the availability of therapeutic monoclonal antibodies, which may avoid the toxic effects of chemotherapy, improve the outcomes when combined with chemotherapy, and provide options for patients with refractory disease. This article reviews the current uses of monoclonal antibodies in B-cell non-Hodgkin's lymphoma.

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OpenAlex reports 439 citations for this work. Citation counts describe recorded attention and do not establish research quality.

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Available abstract

Treatment of B-cell non-Hodgkin's lymphoma has become more successful, largely owing to the availability of therapeutic monoclonal antibodies, which may avoid the toxic effects of chemotherapy, improve the outcomes when combined with chemotherapy, and provide options for patients with refractory disease. This article reviews the current uses of monoclonal antibodies in B-cell non-Hodgkin's lymphoma.

Key concepts: Medicine, Monoclonal antibody, Lymphoma, Chemotherapy, Monoclonal antibody therapy, Monoclonal, Antibody therapy, Disease

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