The effect of repeated episodes of profuse sweating on the human eccrine sweat glands.

Although the physiologic effects of repeated episodes of profuse sweating have been extensively studied in man, nothing is known of the possible anatomic alterations which may occur in the eccrine sweat gland as a result of these stimuli. It has recently been shown, however, that as a result of a single, prolonged episode of profuse sweating the human eccrine sweat gland undergoes characteristic cytologic changes (1). In addition, an orderly, progressive sequence of recovery from these changes has been observed (2).