Mixed Testicular Germ Cell Tumor Presenting as Metastatic Pure Choriocarcinoma Involving Multiple Lung Metastases That Was Effectively Treated with High-dose Chemotherapy

I n t r o d u c t i o nChoriocarcinoma is a highly malignant uncommon tumor of the testis, and it usually occurs as a component of mixed germ cell tumor (1).The testicular enlargement may be subtle, and the patient may present with multiple metastasis.Early metastases are usually found in most of these patients, and they most commonly occur in the lung, liver and brain.There is often marked elevation of the serum levels of human chorionic gonadotropin (hCG) (2).On gross examination, choriocarcinomas of the testis are often small and the involved testes may appear normal.Metastasis from a testicular mixed germ cell tumor as pure choriocarcinoma is also uncommon (3).We report here on one case of metastatic pure choriocarcinoma with aggressive lymph node metastases and multiple pulmonary metastases, and the patient achieved complete remission after high-dose chemotherapy with autologous stem cell transplantation.