CD8+ cutaneous T‐cell lymphoma successfully treated with bexarotene: A case report and review of the literature
Srivalli Gopaluni, Raiza Perzova, Lynn Abbott, Ramsey Farah, Anthony E. Shrimpton, R. Hutchison, Bernard J. Poiesz
Abstract
Srivalli Gopaluni, Raiza Perzova, Lynn Abbott, Ramsey Farah, Anthony E. Shrimpton, R. Hutchison, Bernard J. Poiesz
Abstract
CD8+ cutaneous T-cell lymphoma (CTCL) is a relatively rare subset of the non-Hodgkins lymphomas. Bexarotene has been FDA-approved for the treatment of CTCL, but previous studies have been conducted on CD4+ CTL and there have been no reports about its use in CD8+ CTCL. Herein, we report on a patient whose CD8+ CTCL completely responded to treatment with bexarotene.
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CD8+ cutaneous T-cell lymphoma (CTCL) is a relatively rare subset of the non-Hodgkins lymphomas. Bexarotene has been FDA-approved for the treatment of CTCL, but previous studies have been conducted on CD4+ CTL and there have been no reports about its use in CD8+ CTCL. Herein, we report on a patient whose CD8+ CTCL completely responded to treatment with bexarotene.
Key concepts: Bexarotene, Cutaneous T-cell lymphoma, Medicine, CD8, Mycosis fungoides, Lymphoma, Dermatology, Internal medicine