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2010•New England Journal of MedicineRequires access

Permethrin and Ivermectin for Scabies

Bart J. Currie, James McCarthy

Open publisher page 323 citations

Abstract

A 4-year-old boy is brought to a health center with sores on his arms and legs. He and several siblings receive a diagnosis of scabies. Crusted scabies is diagnosed in an elderly aunt in the same household. The family members are treated with topical permethrin, which disrupts the function of voltage-gated sodium channels in arthropods. The aunt is treated with oral ivermectin, which disrupts the function of chloride ion channels.

About this research paper

What this paper is about

A 4-year-old boy is brought to a health center with sores on his arms and legs. He and several siblings receive a diagnosis of scabies. Crusted scabies is diagnosed in an elderly aunt in the same household. The family members are treated with topical permethrin, which disrupts the function of voltage-gated sodium channels in arthropods. The aunt is treated with oral ivermectin, which disrupts the function of chloride ion channels.

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OpenAlex reports 323 citations for this work. Citation counts describe recorded attention and do not establish research quality.

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Available abstract

A 4-year-old boy is brought to a health center with sores on his arms and legs. He and several siblings receive a diagnosis of scabies. Crusted scabies is diagnosed in an elderly aunt in the same household. The family members are treated with topical permethrin, which disrupts the function of voltage-gated sodium channels in arthropods. The aunt is treated with oral ivermectin, which disrupts the function of chloride ion channels.

Key concepts: Scabies, Ivermectin, Aunt, Permethrin, Medicine, Dermatology, Veterinary medicine, Biology

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