2015•Toxicology and Applied PharmacologyRequires access

Alisol B 23-acetate protects against ANIT-induced hepatotoxity and cholestasis, due to FXR-mediated regulation of transporters and enzymes involved in bile acid homeostasis

Qiang Meng, Xin-li Chen, Changyuan Wang, Qi Liu, Huijun Sun, Pengyuan Sun, Xiaokui Huo, Zhihao Liu, Jihong Yao, Kexin Liu

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Key concepts: Farnesoid X receptor, Cholestasis, Cholesterol 7 alpha-hydroxylase, Multidrug resistance-associated protein 2, Bile acid, Liver injury, Bile Salt Export Pump, CYP8B1

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Alisol B 23-acetate protects against ANIT-induced hepatotoxity and cholestasis, due to FXR-mediated regulation of transporters and enzymes involved in bile acid homeostasis — Research Paper | ScholarLens