A. Simonyan, A. Ayvazyan, V. Vardanyan, L V Kozlovskaya, В. В. Рамеев
Abstract
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Familial Mediterranean fever (FMF) is a hereditary inflammatory disorder. FMF is an autoinflammatory disease caused by mutations in MEFV, a gene which encodes a 781–amino acid protein denoted pyrin. AA-amyloidosis is the main complication of FMF.
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Familial Mediterranean fever (FMF) is a hereditary inflammatory disorder. FMF is an autoinflammatory disease caused by mutations in MEFV, a gene which encodes a 781–amino acid protein denoted pyrin. AA-amyloidosis is the main complication of FMF.
Key concepts: Familial Mediterranean fever, MEFV, Pyrin domain, Amyloidosis, Medicine, AA amyloidosis, Rheumatology, Internal medicine