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1997•Scandinavian Journal of Infectious DiseasesOpen access

Fatal Encephalitis Caused by Mycoplasma pneumoniae in a 9-year-old Girl

Jeroen H. T. Tjhie, Elise M. van de Putte, Krijn Haasnoot, Adriaan J. C. van den Brule, Christina M. J. E. Vandenbroucke‐Grauls

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Abstract

A case of fatal encephalitis in a 9-year-old girl is described. Serology showed high titre antibodies against Mycoplasma pneumoniae. In addition M. pneumoniae was detected in cerebrospinal fluid by polymerase chain reaction. Direct invasion of the central nervous system as opposed to a secondary immunologic reaction to a M. pneumoniae infection of the respiratory tract in the pathogenesis of encephalitis is discussed.

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What this paper is about

A case of fatal encephalitis in a 9-year-old girl is described. Serology showed high titre antibodies against Mycoplasma pneumoniae. In addition M. pneumoniae was detected in cerebrospinal fluid by polymerase chain reaction. Direct invasion of the central nervous system as opposed to a secondary immunologic reaction to a M. pneumoniae infection of the respiratory tract in the pathogenesis of encephalitis is discussed.

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Available abstract

A case of fatal encephalitis in a 9-year-old girl is described. Serology showed high titre antibodies against Mycoplasma pneumoniae. In addition M. pneumoniae was detected in cerebrospinal fluid by polymerase chain reaction. Direct invasion of the central nervous system as opposed to a secondary immunologic reaction to a M. pneumoniae infection of the respiratory tract in the pathogenesis of encephalitis is discussed.

Key concepts: Mycoplasma pneumoniae, Mycoplasmataceae, Encephalitis, Serology, Pathogenesis, Mollicutes, Medicine, Polymerase chain reaction

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