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β2-Microglobulin Amyloidosis: Illustrative Cases

Maria M. Picken, Shiliang Shen

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Abstract

Patients on long-term dialysis tend to develop amyloidosis derived from beta 2-microglobulin. Serum levels of this protein rise in renal insufficiency and remain high in patients on dialysis. The distribution of amyloid deposits in such patients as well as tissue diagnosis, immunohistochemistry, and electron microscopic features are briefly discussed.

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What this paper is about

Patients on long-term dialysis tend to develop amyloidosis derived from beta 2-microglobulin. Serum levels of this protein rise in renal insufficiency and remain high in patients on dialysis. The distribution of amyloid deposits in such patients as well as tissue diagnosis, immunohistochemistry, and electron microscopic features are briefly discussed.

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OpenAlex reports 5 citations for this work. Citation counts describe recorded attention and do not establish research quality.

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Available abstract

Patients on long-term dialysis tend to develop amyloidosis derived from beta 2-microglobulin. Serum levels of this protein rise in renal insufficiency and remain high in patients on dialysis. The distribution of amyloid deposits in such patients as well as tissue diagnosis, immunohistochemistry, and electron microscopic features are briefly discussed.

Key concepts: Beta-2 microglobulin, Amyloidosis, Amyloid (mycology), Dialysis, Medicine, Pathology, Immunohistochemistry, Amyloid fibril

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