2007Critical CareOpen access

Extravascular lung water following resuscitation of hemorrhagic shock in swine: comparison between Ringers' lactate and normal saline

Christopher J. Phillips, Brandon H. Tieu, Daniel Hagg, Martin A. Schreiber

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Abstract

Pulmonary edema is a common consequence of hemorrhagic shock resuscitation. The type and amount of fluid used in resuscitation may be important determinants of the amount of edema formed. Ringers' lactate (RL) and normal saline (NS) remain common resuscitative fluids. These experiments were designed to measure the extravascular lung water (EVLW) after resuscitation from hemorrhagic shock with RL vs NS, to determine whether the fluid type results in differences in the amount of EVLW, and to determine whether there exists a threshold amount of fluid that results in the development of edema.

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Pulmonary edema is a common consequence of hemorrhagic shock resuscitation. The type and amount of fluid used in resuscitation may be important determinants of the amount of edema formed. Ringers' lactate (RL) and normal saline (NS) remain common resuscitative fluids. These experiments were designed to measure the extravascular lung water (EVLW) after resuscitation from hemorrhagic shock with RL vs NS, to determine whether the fluid type results in differences in the amount of EVLW, and to determine whether there exists a threshold amount of fluid that results in the development of edema.

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Available abstract

Pulmonary edema is a common consequence of hemorrhagic shock resuscitation. The type and amount of fluid used in resuscitation may be important determinants of the amount of edema formed. Ringers' lactate (RL) and normal saline (NS) remain common resuscitative fluids. These experiments were designed to measure the extravascular lung water (EVLW) after resuscitation from hemorrhagic shock with RL vs NS, to determine whether the fluid type results in differences in the amount of EVLW, and to determine whether there exists a threshold amount of fluid that results in the development of edema.

Key concepts: Resuscitation, Medicine, Hemorrhagic shock, Shock (circulatory), Saline, Pulmonary edema, Anesthesia, Edema

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