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Felty's Syndrome: Long-Term Follow-up After Splenectomy

RICK A. MOORE, CAROLYN M. BRUNNER, WILLIAM R. SANDUSKY, BYRD S. LEAVELL

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Abstract

The clinical, hematologic, and serologic features, before and after splenectomy, of 15 patients with Felty's syndrome are described. Follow-up periods ranged from 1 to 13½ years. Splenectomy relieved the neutropenia in 66% of the patients, with no late relapses. The frequency of infections was markedly decreased in most of the patients who had a return of the neutrophil count to normal after splenectomy. The indications and contraindications for splenectomy are discussed.

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What this paper is about

The clinical, hematologic, and serologic features, before and after splenectomy, of 15 patients with Felty's syndrome are described. Follow-up periods ranged from 1 to 13½ years. Splenectomy relieved the neutropenia in 66% of the patients, with no late relapses. The frequency of infections was markedly decreased in most of the patients who had a return of the neutrophil count to normal after splenectomy. The indications and contraindications for splenectomy are discussed.

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OpenAlex reports 77 citations for this work. Citation counts describe recorded attention and do not establish research quality.

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Available abstract

The clinical, hematologic, and serologic features, before and after splenectomy, of 15 patients with Felty's syndrome are described. Follow-up periods ranged from 1 to 13½ years. Splenectomy relieved the neutropenia in 66% of the patients, with no late relapses. The frequency of infections was markedly decreased in most of the patients who had a return of the neutrophil count to normal after splenectomy. The indications and contraindications for splenectomy are discussed.

Key concepts: Splenectomy, Medicine, Felty's syndrome, Neutropenia, Surgery, Serology, Internal medicine, Gastroenterology

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