Apparent response of refractory post‐transfusion purpura to splenectomy
C. Casey Cunningham, Stuart E. Lind
Abstract
C. Casey Cunningham, Stuart E. Lind
Abstract
Post transfusion purpura (PTP) is a rare disorder characterized by the abrupt onset of severe thrombocytopenia following transfusion. A patient with PTP and massive bleeding was refractory to corticosteroids, gamma globulin, and plasma exchange but developed an immediate and sustained rise in platelet count following splenectomy. Splenectomy may be a useful therapeutic modality in patients with refractory PTP.
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Post transfusion purpura (PTP) is a rare disorder characterized by the abrupt onset of severe thrombocytopenia following transfusion. A patient with PTP and massive bleeding was refractory to corticosteroids, gamma globulin, and plasma exchange but developed an immediate and sustained rise in platelet count following splenectomy. Splenectomy may be a useful therapeutic modality in patients with refractory PTP.
Key concepts: Splenectomy, Refractory (planetary science), Medicine, Purpura (gastropod), Platelet, Platelet transfusion, Gamma globulin, Surgery