Chloramine-T (SodiumN-Chloro-p-toluenesulfonamide)

All articles of this category Introduction Sodium N -chloro- p -toluenesulfonamide, commonly known as Chloramine-T, has diverse chemical properties. Several other N -halogeno- N -metalloarylsulfonamides are also available, such as Chloramine B, Bromamine T, Bromamine B, and Iodamine-T. Chloramine-T in the hydrate form has been used in various types of chemical reactions more extensively than others in this group. It is commercially available, inexpensive, water-tolerant, non-toxic, easy to handle, and can be used without further purification. The usefulness of Chloramine-T is that it behaves as a source of both ‘halonium’ ion as well as a ‘nitrogen ­anion’. As a result, these reagents react with a surprising range of functional groups, leading to an array of mole­cular transformations. The synthetic applications of Chloramine-T have been well-documented for amino­hydroxylation, aminochalcogenation of alkenes, allylic aminations, and aziridinations.