ChemInform Abstract: Synthesis of Fused Heterocycles via Preferential Hydroamination of O‐Haloarylalkynes over N‐Arylation and Successive Intramolecular C—C Bond Formation.
Rajeev Ranjan Jha, Abhinandan K. Danodia, Akhilesh K. Verma
Abstract
Rajeev Ranjan Jha, Abhinandan K. Danodia, Akhilesh K. Verma
Abstract
Abstract A Cu‐catalyzed tandem approach for the synthesis of indolo‐ and pyrrolonaphthyridines via regioselective addition of indoles or pyrrole to 3‐bromo‐2‐ethynylpyridines (II) followed by intramolecular cyclization is presented.
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Abstract A Cu‐catalyzed tandem approach for the synthesis of indolo‐ and pyrrolonaphthyridines via regioselective addition of indoles or pyrrole to 3‐bromo‐2‐ethynylpyridines (II) followed by intramolecular cyclization is presented.
Key concepts: Chemistry, Hydroamination, Intramolecular force, Medicinal chemistry, Combinatorial chemistry, Stereochemistry