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1972•The Journal of Clinical Endocrinology & MetabolismRequires access

The Possible Influence of Puberty on the Release of Growth Hormone in Three Males with Apparent Isolated Growth Hormone Deficiency

Robert Penny, Robert M. Blizzard

Open publisher page 38 citations

Abstract

Three males with short stature and delayed bone ages were found to have abnormal growth hormone responses to hypoglycemia and arginine infusion before puberty. After the onset of puberty they were found to have normal GH responses to hypoglycemia and/or arginine infusion. These findings are in accord with the suggestion that androgens may influence growth hormone release in some individuals who appear to have isolated growth hormone deficiency.

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What this paper is about

Three males with short stature and delayed bone ages were found to have abnormal growth hormone responses to hypoglycemia and arginine infusion before puberty. After the onset of puberty they were found to have normal GH responses to hypoglycemia and/or arginine infusion. These findings are in accord with the suggestion that androgens may influence growth hormone release in some individuals who appear to have isolated growth hormone deficiency.

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OpenAlex reports 38 citations for this work. Citation counts describe recorded attention and do not establish research quality.

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Available abstract

Three males with short stature and delayed bone ages were found to have abnormal growth hormone responses to hypoglycemia and arginine infusion before puberty. After the onset of puberty they were found to have normal GH responses to hypoglycemia and/or arginine infusion. These findings are in accord with the suggestion that androgens may influence growth hormone release in some individuals who appear to have isolated growth hormone deficiency.

Key concepts: Endocrinology, Internal medicine, Growth hormone, Hypoglycemia, Short stature, Growth hormone deficiency, Hormone, Arginine

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