2000•Dermatologic SurgeryRequires access

Hematoxylin and Safranin O Staining of Frozen Sections

David D. Tran, Martin L. Golick, Harold S. Rabinovitz, Daniel Rivlin, George W. Elgart, Barbara Nordlow

Abstract

Currently the hematoxylin and eosin staining procedure is the most popular among Mohs surgeons for histology. However, safranin O, a cheaper and relatively safer stain which is predominantly used for plant histology, should be considered as it offers similar or improved accuracy in the diagnosis of frozen sections of basal and squamous cell carcinomas.

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Available abstract

Key concepts: H&E stain, Safranin, Histology, Staining, Stain, Medicine, Pathology, Frozen section procedure