Biotransformation of (-)-Maalioxide by Aspergillus niger and Aspergillus cellulosae
Toshihiro Hashimoto, Yoshiaki Noma, Yoshiaki Gotoh, Masami Tanaka, Shigeru Takaoka, Yoshinori Asakawa
Abstract
Toshihiro Hashimoto, Yoshiaki Noma, Yoshiaki Gotoh, Masami Tanaka, Shigeru Takaoka, Yoshinori Asakawa
Abstract
A sesquiterpene cyclic ether, (-)-maalioxide (1) from the liverwort Plagiochila sciophila was biotransformed by Aspergillus niger and A. cellulosae to afford the structurally interesting compounds.The stereostructures of the metabolites were established by a combination of high resolution NMR spectrum, X-Ray crystallographic analysis and the chemical reaction.
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A sesquiterpene cyclic ether, (-)-maalioxide (1) from the liverwort Plagiochila sciophila was biotransformed by Aspergillus niger and A. cellulosae to afford the structurally interesting compounds.The stereostructures of the metabolites were established by a combination of high resolution NMR spectrum, X-Ray crystallographic analysis and the chemical reaction.
Key concepts: Aspergillus niger, Biotransformation, Chemistry, Sesquiterpene, Stereochemistry, Aspergillus, Ether, Nuclear magnetic resonance spectroscopy