2004HeterocyclesOpen access

Biotransformation of (-)-Maalioxide by Aspergillus niger and Aspergillus cellulosae

Toshihiro Hashimoto, Yoshiaki Noma, Yoshiaki Gotoh, Masami Tanaka, Shigeru Takaoka, Yoshinori Asakawa

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Abstract

A sesquiterpene cyclic ether, (-)-maalioxide (1) from the liverwort Plagiochila sciophila was biotransformed by Aspergillus niger and A. cellulosae to afford the structurally interesting compounds.The stereostructures of the metabolites were established by a combination of high resolution NMR spectrum, X-Ray crystallographic analysis and the chemical reaction.

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What this paper is about

A sesquiterpene cyclic ether, (-)-maalioxide (1) from the liverwort Plagiochila sciophila was biotransformed by Aspergillus niger and A. cellulosae to afford the structurally interesting compounds.The stereostructures of the metabolites were established by a combination of high resolution NMR spectrum, X-Ray crystallographic analysis and the chemical reaction.

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Available abstract

A sesquiterpene cyclic ether, (-)-maalioxide (1) from the liverwort Plagiochila sciophila was biotransformed by Aspergillus niger and A. cellulosae to afford the structurally interesting compounds.The stereostructures of the metabolites were established by a combination of high resolution NMR spectrum, X-Ray crystallographic analysis and the chemical reaction.

Key concepts: Aspergillus niger, Biotransformation, Chemistry, Sesquiterpene, Stereochemistry, Aspergillus, Ether, Nuclear magnetic resonance spectroscopy

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