Serological Analysis of Human Leptospirosis in the Philippines
Toshiyuki Masuzawa, Louella A. Dancel, Masaki Miyake, Yasutake Yanagihara
Abstract
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Toshiyuki Masuzawa, Louella A. Dancel, Masaki Miyake, Yasutake Yanagihara
Abstract
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Leptospirosis in the Philippines is an underrepresented disease. To achieve an accurate means of serodiagnosis, we demonstrated antibodies to the prevalent Leptospira serovars in sera of 71 patients from three major hospitals in Manila by the microscopic agglutination test and Western blot analysis. Sera of 53 patients contained antibody against 8 serovars poi, tarassovi, manilae, pyrogenes, australis, grippotyphosa, javanica, and autumnalis.
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Leptospirosis in the Philippines is an underrepresented disease. To achieve an accurate means of serodiagnosis, we demonstrated antibodies to the prevalent Leptospira serovars in sera of 71 patients from three major hospitals in Manila by the microscopic agglutination test and Western blot analysis. Sera of 53 patients contained antibody against 8 serovars poi, tarassovi, manilae, pyrogenes, australis, grippotyphosa, javanica, and autumnalis.
Key concepts: Leptospirosis, Serotype, Leptospira, Serology, Direct agglutination test, Biology, Antibody, Agglutination (biology)