2010•Unpublished venueRequires access

Integrated Optical Coherence Tomography (OCT) and Fluorescence Laminar Optical Tomography (FLOT) for Depth-resolved Subsurface Cancer Imaging

Yu Chen, Shuai Yuan, Jerry Wierwille, Chao‐Wei Chen, Tiffany R. Blackwell, Paul T. Winnard, Venu Raman, Kristine Glunde

Abstract

We developed a combined optical coherence tomography (OCT) and fluorescence laminar optical tomography (FLOT) system for co-registered depth-resolved structural and molecular imaging. Experimental results using a mouse model with human breast cancer xenograft are presented.

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Key concepts: Optical coherence tomography, Diffuse optical imaging, Optical tomography, Tomography, Materials science, Fluorescence-lifetime imaging microscopy, Optics, Fluorescence