1969•EndocrinologyRequires access

Δ5-3β-Hydroxysteroid Dehydrogenase in Toad Testis: Synergistic Action of Ascorbic Acid and Luteinizing Hormone

NARENDRA MOHAN BISWAS

Abstract

Administration of ascorbic acid (AsA) to normal toads increased testicular Δ5-3β-hydroxysteroid dehydrogenase which was demonstrated in both the tubular and Leydig cells. After hypophysectomy, the enzymic activity was much diminished in the testes. AsA and luteinizing hormone (LH) induced testicular enzyme activity in hypophysectomized toads18 hr after treatment. Injection of AsA or 55 jug of LH alone was unable to stimulate the enzyme in testes of hypophysectomized toads. The evidence indicates that AsA in conjunction with LH augments the testicular Δ5-3β-hydroxysteroid dehydrogenase activity. (Endocrinology85: 981, 1969)

About this research paper

What this paper is about

Why it matters

OpenAlex reports 20 citations for this work. Citation counts describe recorded attention and do not establish research quality.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Key concepts: Internal medicine, Endocrinology, Hypophysectomy, Luteinizing hormone, Ascorbic acid, Toad, Dehydrogenase, Hydroxysteroid dehydrogenase