An association between schistosomes and contrapsin, a mouse serine protease inhibitor (serpin)
Jay Modha, Vaishu Parikh, Jack Gauldie, Michael J. Doenhoff
Abstract
Jay Modha, Vaishu Parikh, Jack Gauldie, Michael J. Doenhoff
Abstract
An antigen in homogenates of adult Schistosoma mansoni worms grown in mice, and immunoprecipitated by polyspecific rabbit antiserum, has been identified as contrapsin, a mouse serine protease inhibitor (serpin). In the serum of some mice infected with S. mansoni contrapsin was found with altered immunoelectrophoretic characteristics when compared with contrapsin from uninfected mice.
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An antigen in homogenates of adult Schistosoma mansoni worms grown in mice, and immunoprecipitated by polyspecific rabbit antiserum, has been identified as contrapsin, a mouse serine protease inhibitor (serpin). In the serum of some mice infected with S. mansoni contrapsin was found with altered immunoelectrophoretic characteristics when compared with contrapsin from uninfected mice.
Key concepts: Serpin, Biology, Serine protease, Schistosoma mansoni, Serine Proteinase Inhibitors, Antiserum, Proteases, Protease